Effects of Ions-DNA Interactions on Surface Charge of Graphene FieldEffect Transistor

Sandrasagran, Gohvinath (2021) Effects of Ions-DNA Interactions on Surface Charge of Graphene FieldEffect Transistor. [Final Year Project] (Submitted)

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Graphene Field Effect Transistors (GFET) are currently being used in many sensing
applications due to its high sensitivity and good selectivity. In this project, GFET
properties and characteristics will be discussed and compared with other field effect
transistors (FET). More importantly, biomolecular electrostatic calculation will be
carried out to determine mean electrostatic potential energy, binding energy, and
solvation energy. These biomolecular electrostatic calculations will be done using the
Poisson-Boltzmann equation coded in MATLAB. Next, study on how these
parameters affect ion-DNA interaction and the surface charge on GFET will be
carried out by modelling the GFET based on drift-diffusion (DD) model using
MATLAB. From the Poisson-Boltzmann equation, the electrostatic potential energy
contained within a single strandguanine DNA is found to be 120213 kJol/mol while
binding energy and solvation energy are 119991 kJol/mol and 3509.09 kJol/mol,
respectively. From drift-diffusion model, the potential on the surface that is needed to
cause a shift in the charge neutrality point by 3.5V, is estimated to be -15mV. The
outcome of this project should be able to shed some light on how the sensitivity and
selectivity of GFET can be furtherimproved.

Item Type: Final Year Project
Subjects: T Technology > TK Electrical engineering. Electronics Nuclear engineering
Departments / MOR / COE: Engineering > Electrical and Electronic
Depositing User: Mr Ahmad Suhairi Mohamed Lazim
Date Deposited: 11 Mar 2022 04:20
Last Modified: 11 Mar 2022 04:20
URI: http://utpedia.utp.edu.my/id/eprint/23041

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