Molybdenum Disulphide/Cellulose Acetate Nanofiber Composite on Screen Printed Electrodes for Determining Cardiac Disease by Electrochemical Impedance Spectroscopy

Acute Myocardial Infraction (AMI) where currently ranked at top for causes of death worldwide, can be diagnose by detecting the concentration level of Troponin I in human blood. However, current problem reflects onto poor diagnose test such as Enzyme-Linked Immunosorbent Assay (ELISAs) because of expensive utilization cost and time limitation in diagnosing and treatment. Thus, to mitigate the number of deaths caused by cardiovascular disease, a nano-biosensor to detect troponin level in blood, developed by optimizing the active material in the biosensor. Molybdenum Disulphide (MoS2) has great sensing abilities where it has an optimum band gap property as it has efficient conductivity although being a semiconductor transition metal dichalcogenide. With the aid of Cellulose Acetate (CA), synthesis of nanofiber from MoS2 mixed with CA can be done with ease by electrospinning method. Characterization under Field Emission Scanning Electron Microscope (FESEM) exhibited the nanofiber with diameter of 200nm and analysed the morphology structure to capture the layered nanofiber.