Gene Prediction System ·

With the increasingly popularity of genome sequencing, transfonning such
raw sequence data into knowledge remains a hard task. This project will develop
an application for gene prediction using development tools such as Perl and PHP.
This project also will identify stretches of sequence for genomic DNA that is
biologically functional including protein coding regions. There are 3 steps involve
which are transcription, splicing and translation. Transcription is the process of
copying DNA to RNA Meanwhile, splicing is modification of genetic
) infonnation after a few transcriptions. It will determine introns (useless
infonnation) and exons (useful infonnation) in DNA sequence. Hidden Markov
Model which is a mathematical functional will be used in this step in order to
predict the DNA sequence. The introns will be removed and exons will be
combined together to produce mRNA. The final step is translation which is the
process by which mRNA is translated into proteins. The protein sequence is the
final output of Gene Prediction System. More knowledge on gene prediction will
be explored in order to get better unde~tanding of how gene prediction works.